Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 166
interventional 70
Observational 84
Registry 12

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 22
Other 9
Drug 8
Behavioral 7
Drug|placebo 4
Device|Drug 3
Device|Procedure 3
Dietary Supplement 3
Procedure 3
Behavioral|Drug 1
Behavioral|Genetic|Procedure 1
Device|Drug|Procedure 1
Device|Other 1
Diagnostic Test 1
Dietary Supplement|Other 1
Drug|Procedure 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 24
NA 13
Canada 4
Germany 4
Denmark 3
France 3
Netherlands 2
Sweden 2
United Kingdom 2
Argentina|Belarus|Brazil|China|Colombia|Egypt|India|Korea, Republic of|Malaysia|Mexico|Russian Federation|Singapore|South Africa|Taiwan|Tunisia|United Arab Emirates 1
Australia|United Kingdom 1
Austria|Czech Republic|Germany|Hungary|Israel|Latvia|New Zealand|Poland|Slovakia|Spain|Switzerland 1
Belgium 1
China|Japan|Korea, Republic of|Taiwan 1
Greece 1
Japan 1
Korea, Republic of 1
Singapore 1
Switzerland 1
United States|Australia|Czechia|Germany|Hungary|Latvia|Malaysia|New Zealand|Poland|Russian Federation|Singapore|Slovakia|Switzerland 1
United States|Austria|Canada|Italy|Japan|Korea, Republic of|Portugal|Spain|United Kingdom 1
United States|Canada|Germany|Spain 1

Sites per Study

Site_count Study_Count
1 49
2 4
3 2
4 1
5 1
10 3
11 1
14 1
16 1
23 1
30 1
36 1
37 1
41 1
93 1
150 1

Phase

Phase Study_Count
N/A 43
Phase 3 14
Phase 4 6
Phase 1 3
Phase 2 3
Phase 1/Phase 2 1

Number of Arms

Number_of_Arms Count_of_Studies
1 14
2 30
3 8
4 1
6 1
8 1
NA 15

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.3 Phase.4
Min. 6.000 150.0000 8 10 7.0 77.000
1st Qu. 55.500 155.0000 8 33 122.0 154.500
Median 164.000 160.0000 8 56 295.5 207.500
Mean 2027.558 167.3333 8 42 1914.0 3189.333
3rd Qu. 465.000 176.0000 8 58 2939.5 432.250
Max. 69656.000 192.0000 8 60 7001.0 18000.000

Trial Group Type

group_type Group_Count
Experimental 60
Active Comparator 26
No Intervention 15
NA 15
Placebo Comparator 10
Other 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 34
Single Group Assignment 21
NA 9
Crossover Assignment 4
Factorial Assignment 1
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 30
Prevention 15
Diagnostic 5
Health Services Research 4
Other 4
Supportive Care 4
Basic Science 3
NA 3
Screening 2

Observational Studies

Studies by Country

Country Study_Count
United States 21
NA 19
Germany 6
France 5
Canada 3
Italy 3
Korea, Republic of 3
Finland 2
Spain 2
United Kingdom 2
Austria 1
Bangladesh|Brunei Darussalam|China|Egypt|India|Indonesia|Korea, Republic of|Malaysia|Pakistan|Philippines|Saudi Arabia|Singapore|South Africa|Taiwan|Thailand|Tunisia 1
Belgium|Germany|Greece|Netherlands 1
China 1
Denmark 1
Germany|Switzerland 1
Japan 1
Jordan 1
Norway 1
Poland 1
Switzerland 1
United States|Australia|Canada 1
United States|Austria|France|Germany 1
United States|Canada|France 1
United States|Canada|Israel 1
United States|Canada|Puerto Rico 1
United States|Israel 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 59
2 7
3 2
4 3
5 2
6 1
12 1
21 1
34 1
52 1
55 1
64 1
78 1
87 1
90 1
111 1

Enrollment Metrics

Measure Observational
Min 25.0
1st Qu 100.0
Median 400.0
Mean 434078.0
3rd Qu 1681.5
Max 31000000.0

Observation Model

observational_model Study_Count
Cohort 51
NA 11
Case Control 8
Case-Control 5
Case-Only 4
Other 4
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 52
Retrospective 13
NA 11
Other 5
Cross-Sectional 3

Registries

Studies by Country

Country Study_Count
Canada 2
France 2
Australia 1
Germany 1
Italy 1
Korea, Republic of 1
NA 1
Netherlands 1
Poland 1
United States 1

Sites per Study

Site_count Study_Count
1 8
2 2
3 1
10 1

Enrollment Metrics

Measure Registries
Min 19.000
1st Qu 412.500
Median 641.500
Mean 3092.917
3rd Qu 1550.000
Max 20000.000

Registry Model

observational_model Study_Count
Cohort 10
Family-Based 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 11
Other 1

Follow-up

target_duration Study_Count
1 Year 2
2 Years 2
1 Day 1
1 Month 1
20 Years 1
24 Months 1
3 Months 1
3 Years 1
32 Months 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03305250 Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease https://ClinicalTrials.gov/show/NCT03305250 Recruiting University Hospital Birmingham NHS Foundation Trust 2022-01-31
NCT03207373 Stress ECG Test for the Evaluation of the Risk of Sudden Cardiac Death in a Paediatric Cohort With WPW Pattern https://ClinicalTrials.gov/show/NCT03207373 Enrolling by invitation University Children’s Hospital, Zurich 2021-02-28
NCT03101787 Early Initiation of Extracorporeal Life Support in Refractory OHCA https://ClinicalTrials.gov/show/NCT03101787 Recruiting Maastricht University Medical Center 2020-07-31
NCT03065647 ECPR for Refractory Out-Of-Hospital Cardiac Arrest https://ClinicalTrials.gov/show/NCT03065647 Completed University of Michigan 2020-03-05
NCT02992873 The Scandinavian AED and Mobile Bystander Activation Trial https://ClinicalTrials.gov/show/NCT02992873 Recruiting Karolinska Institutet 2020-04-30
NCT02923726 Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP https://ClinicalTrials.gov/show/NCT02923726 Recruiting Boston Scientific Corporation 2025-10-31
NCT02874469 Impact of an Intensive Care Diary on Post-traumatic Stress Disorder After a Resuscitated Sudden Death https://ClinicalTrials.gov/show/NCT02874469 Recruiting University Hospital, Lille 2023-11-30
NCT02848781 Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial https://ClinicalTrials.gov/show/NCT02848781 Recruiting University of Chicago 2021-02-28
NCT02845531 Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifesting as Aborted Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT02845531 Recruiting Asan Medical Center 2022-12-31
NCT02819973 Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy https://ClinicalTrials.gov/show/NCT02819973 Completed Duke University 2020-01-28
NCT00000492 Beta-Blocker Heart Attack Trial (BHAT) https://ClinicalTrials.gov/show/NCT00000492 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT02738749 Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study https://ClinicalTrials.gov/show/NCT02738749 Recruiting Rhode Island Hospital 2019-07-31
NCT02668900 Decision Support for Adults Facing Implantable Cardioverter-Defibrillator Pulse Generator Replacement https://ClinicalTrials.gov/show/NCT02668900 Completed Ottawa Heart Institute Research Corporation 2018-04-30
NCT01319110 Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation https://ClinicalTrials.gov/show/NCT01319110 Completed Beth Israel Deaconess Medical Center 2011-12-31
NCT02099721 Improve Sudden Cardiac Arrest Study https://ClinicalTrials.gov/show/NCT02099721 Completed Medtronic Cardiac Rhythm and Heart Failure 2018-07-15
NCT02026102 A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs) https://ClinicalTrials.gov/show/NCT02026102 Completed University of Colorado, Denver 2016-08-31
NCT02014961 Worm Study: Modifier Genes in Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT02014961 Recruiting Maastricht University Medical Center 2025-04-30
NCT01949025 Prevention of Serious Adverse Events in Acute Care Hospitals by Afferent Limb and Response Method Intervention - the ALARM Intervention Study. https://ClinicalTrials.gov/show/NCT01949025 Completed Universiteit Antwerpen 2015-09-30
NCT01916408 The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon https://ClinicalTrials.gov/show/NCT01916408 Completed Technische Universität München 2014-01-31
NCT01876173 Feasibility Testing of Decision Support for Patients Who Are Candidates for an Implantable Defibrillator https://ClinicalTrials.gov/show/NCT01876173 Completed McMaster University 2014-09-30
NCT01842035 Heart Rate Response to Regadenoson and Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT01842035 Active, not recruiting University of Alabama at Birmingham 2020-04-30
NCT01809652 Feasibility Study of Remote Support for Implantable Pulse Generator (IPG)/Implantable Cardioverter Defibrillator (ICD) Implant https://ClinicalTrials.gov/show/NCT01809652 Completed Medtronic Cardiac Rhythm and Heart Failure 2014-04-30
NCT01789554 The Use of Mobile Phones in Out of Hospital Cardiac Arrest to Increase Bystander CPR https://ClinicalTrials.gov/show/NCT01789554 Completed Karolinska Institutet 2013-12-31
NCT01774812 Vitamin D and Cardiac Autonomic Tone in Hemodialysis https://ClinicalTrials.gov/show/NCT01774812 Completed University of Calgary 2015-03-31
NCT01749202 Effects of Stearidonic Acid-Containing Foods on Eicosapentaenoic Acid Levels in Red Blood Cells and Omega-3 Index https://ClinicalTrials.gov/show/NCT01749202 Completed Solae, LLC 2011-05-31
NCT01665755 To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients https://ClinicalTrials.gov/show/NCT01665755 Completed Singapore General Hospital 2018-03-31
NCT04387435 Optimization of VNS in Epileptic Patients to Induce Cardioprotection https://ClinicalTrials.gov/show/NCT04387435 Active, not recruiting University of California, Los Angeles 2021-06-30
NCT04352816 Magnetocardiography (MCG) Parameters in the Prediction of Future ICD Therapy https://ClinicalTrials.gov/show/NCT04352816 Recruiting University Hospitals Coventry and Warwickshire NHS Trust 2021-04-30
NCT04132466 ASSURE WCD Clinical Evaluation - Conversion Efficacy Study https://ClinicalTrials.gov/show/NCT04132466 Recruiting Kestra Medical Technologies, Inc. 2020-04-30
NCT04101253 SCREENING FOR THE IMPLANTATION OF A SUBCUTANEOUS IMPLANTABLE AUTOMATIC DEFIBRILLATOR https://ClinicalTrials.gov/show/NCT04101253 Recruiting Centre Hospitalier de PAU 2021-01-29
NCT04036695 Arrhythmia in Hemodialysis Patients https://ClinicalTrials.gov/show/NCT04036695 Recruiting Lawson Health Research Institute 2021-08-30
NCT03887052 ASSURE WCD Clinical Evaluation - Detection and Safety Study https://ClinicalTrials.gov/show/NCT03887052 Completed Kestra Medical Technologies, Inc. 2019-06-18
NCT03700125 Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 ) https://ClinicalTrials.gov/show/NCT03700125 Recruiting Barts & The London NHS Trust 2020-09-30
NCT03588286 Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) https://ClinicalTrials.gov/show/NCT03588286 Recruiting Western Sydney Local Health District 2024-12-31
NCT04462887 Nursing Interventions Following Sudden Cardiac Arrest https://ClinicalTrials.gov/show/NCT04462887 Completed University of Washington 2003-12-31
NCT03504839 Same Day Subcutaneous ICD And Send Home (DASH) https://ClinicalTrials.gov/show/NCT03504839 Completed Ohio State University 2019-04-12
NCT01074034 REASSURE AV Registry https://ClinicalTrials.gov/show/NCT01074034 Completed Boston Scientific Corporation 2011-06-30
NCT01038440 Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood Cells https://ClinicalTrials.gov/show/NCT01038440 Completed Solae, LLC 2010-03-31
NCT00998218 Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction https://ClinicalTrials.gov/show/NCT00998218 Completed Aspirus Heart and Vascular Institute-Research and Education 2010-12-31
NCT00947310 Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy https://ClinicalTrials.gov/show/NCT00947310 Completed Boston Scientific Corporation 2012-08-31
NCT00944775 Exercise and Cardiac Measures in Dialysis Patients https://ClinicalTrials.gov/show/NCT00944775 Completed Aristotle University Of Thessaloniki 2008-05-31
NCT00933218 Beer, Marathon, Genetics, Inflammation and the Cardiovascular System: Be-MaGIC-Trial https://ClinicalTrials.gov/show/NCT00933218 Completed Technische Universität München 2009-11-30
NCT00845286 Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial https://ClinicalTrials.gov/show/NCT00845286 Completed Technische Universität München 2014-03-31
NCT01325870 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest https://ClinicalTrials.gov/show/NCT01325870 Completed Advanced Circulatory Systems 2012-12-31
NCT03291145 Exploring Mechanisms and Morphology of QT Interval Prolongation https://ClinicalTrials.gov/show/NCT03291145 Completed Herlev and Gentofte Hospital 2018-06-27
NCT03916341 Smoking and Ventricular Repolarization https://ClinicalTrials.gov/show/NCT03916341 Recruiting University of California, Los Angeles 2022-04-10
NCT00748111 Thrombus and Inflammation Study in Sudden Cardiac DEath https://ClinicalTrials.gov/show/NCT00748111 Completed Assistance Publique - Hôpitaux de Paris 2012-04-30
NCT00729430 Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging https://ClinicalTrials.gov/show/NCT00729430 Completed Brigham and Women’s Hospital 2013-10-31
NCT00626093 ‘Effect of CRT on Defibrillation Threshold Estimates’ Study https://ClinicalTrials.gov/show/NCT00626093 Completed Abbott Medical Devices 2010-04-30
NCT00619593 Survival of Patients With Primary Prophylactic ICD Indication https://ClinicalTrials.gov/show/NCT00619593 Completed Biotronik SE & Co. KG 2014-04-30
NCT00586378 Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study https://ClinicalTrials.gov/show/NCT00586378 Completed ELA Medical, Inc. 2009-12-31
NCT00560768 Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications https://ClinicalTrials.gov/show/NCT00560768 Completed LivaNova 2012-08-31
NCT00534300 Intravenous n-3 Fatty Acids and Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillator (ICD)-Pacemaker https://ClinicalTrials.gov/show/NCT00534300 Completed Aalborg University Hospital 2008-06-30
NCT00478933 DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients. https://ClinicalTrials.gov/show/NCT00478933 Completed Medtronic Bakken Research Center 2012-07-31
NCT00382928 Automatic External Defibrillation Monitoring in Cardiac Arrest https://ClinicalTrials.gov/show/NCT00382928 Completed Atlanta Research and Education Foundation 2009-09-30
NCT00311181 POWER (Pulse Width Optimized Waveform Evaluation Trial) https://ClinicalTrials.gov/show/NCT00311181 Completed Abbott Medical Devices 2008-04-30
NCT00259025 Intravenous n-3 Fatty Acids and Sudden Cardiac Death in Hemodialysis Patients https://ClinicalTrials.gov/show/NCT00259025 Completed Aalborg University Hospital 2007-07-31
NCT00251134 OMEGA-Study: Effect of Omega 3-Fatty Acids on the Reduction of Sudden Cardiac Death After Myocardial Infarction https://ClinicalTrials.gov/show/NCT00251134 Completed Stiftung Institut fuer Herzinfarktforschung 2008-06-30
NCT00231738 Protective Effect of EPA on Cardiovascular Events https://ClinicalTrials.gov/show/NCT00231738 Completed Kobe University NA
NCT00226681 Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD) https://ClinicalTrials.gov/show/NCT00226681 Completed National Institute of Nursing Research (NINR) 2004-08-31
NCT00187187 DAVID II (Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial II) https://ClinicalTrials.gov/show/NCT00187187 Completed Abbott Medical Devices 2007-09-30
NCT00047411 Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest https://ClinicalTrials.gov/show/NCT00047411 Completed National Heart, Lung, and Blood Institute (NHLBI) 2007-09-30
NCT00004560 Public Access Defibrillation (PAD) Community Trial https://ClinicalTrials.gov/show/NCT00004560 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000609 Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) https://ClinicalTrials.gov/show/NCT00000609 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000540 Coronary Artery Bypass Graft (CABG) Patch Trial https://ClinicalTrials.gov/show/NCT00000540 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000531 Antiarrhythmics Versus Implantable Defibrillators (AVID) https://ClinicalTrials.gov/show/NCT00000531 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000526 Cardiac Arrhythmia Suppression Trial (CAST) https://ClinicalTrials.gov/show/NCT00000526 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000525 Diuretics, Hypertension, and Arrhythmias Clinical Trial https://ClinicalTrials.gov/show/NCT00000525 Completed University of California, San Francisco 1989-09-30
NCT00000518 Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) https://ClinicalTrials.gov/show/NCT00000518 Completed University of Utah NA
NCT00000480 Multicenter Unsustained Tachycardia Trial (MUSTT) https://ClinicalTrials.gov/show/NCT00000480 Completed National Heart, Lung, and Blood Institute (NHLBI) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03366181 Anti Arrhythmic Therapies and Sudden Cardiac Deaths https://ClinicalTrials.gov/show/NCT03366181 Completed University of Campania “Luigi Vanvitelli” 2017-11-20
NCT03248557 Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT03248557 Recruiting Hospital San Carlos, Madrid 2020-12-31
NCT03185832 Heart Failure and Sudden Cardiac Death Japan Registry https://ClinicalTrials.gov/show/NCT03185832 Active, not recruiting Boston Scientific Corporation 2020-08-31
NCT03079414 The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest https://ClinicalTrials.gov/show/NCT03079414 Recruiting Western University, Canada 2020-03-30
NCT03049254 Mayo AVC Registry and Biobank https://ClinicalTrials.gov/show/NCT03049254 Recruiting Mayo Clinic 2022-12-31
NCT03016754 Heart Failure Optimization Study https://ClinicalTrials.gov/show/NCT03016754 Recruiting Zoll Medical Corporation 2020-12-31
NCT02894580 Primary Prevention of Sudden Cardiac Death (PREV-DEATH) https://ClinicalTrials.gov/show/NCT02894580 Completed Centre Hospitalier Régional Metz-Thionville 2015-06-30
NCT02816047 Austrian Wearable Cardioverter Defibrillator Registry https://ClinicalTrials.gov/show/NCT02816047 Recruiting Medical University of Graz 2020-12-31
NCT02500108 Domperidone and Risk of Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT02500108 Completed Canadian Network for Observational Drug Effect Studies, CNODES 2015-06-30
NCT03387072 CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT03387072 Recruiting Nantes University Hospital 2021-03-31
NCT02473679 Influence of the Education in Layperson in Out of Hospital Resuscitation https://ClinicalTrials.gov/show/NCT02473679 Completed University of Zurich 2016-07-31
NCT02349087 EEG in Resuscitated In-hospital Patients https://ClinicalTrials.gov/show/NCT02349087 Recruiting Kuopio University Hospital 2018-12-31
NCT02298543 Coronary Spasm Presenting Aborted Sudden Cardiac Death, the Multicenter Registry https://ClinicalTrials.gov/show/NCT02298543 Completed Asan Medical Center 2015-09-30
NCT02176174 Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study https://ClinicalTrials.gov/show/NCT02176174 Completed University College, London 2016-08-31
NCT02058771 Utilising Lifemap to Investigate Malignant Arrhythmia Therapy https://ClinicalTrials.gov/show/NCT02058771 Recruiting University Hospitals, Leicester 2022-11-30
NCT02045043 Genetic Risk Assessment of Defibrillator Events https://ClinicalTrials.gov/show/NCT02045043 Completed University of Iowa 2012-06-30
NCT01596595 Longitudinal Surveillance Study of the 4-SITE Lead/Header System https://ClinicalTrials.gov/show/NCT01596595 Completed Boston Scientific Corporation 2020-02-18
NCT01944514 Implantable Cardioverter Defibrillators - Improving Risk Stratification https://ClinicalTrials.gov/show/NCT01944514 Completed University Hospitals, Leicester 2012-11-30
NCT01919983 Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden Death https://ClinicalTrials.gov/show/NCT01919983 Completed Johns Hopkins University 2014-09-30
NCT01907633 An Observational Study to Assess the Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Users of Proton Pump Inhibitors, and Users of Metoclopramide https://ClinicalTrials.gov/show/NCT01907633 Completed Janssen Research & Development, LLC 2013-12-31
NCT01790841 DF4 Master Study (Safety and Efficacy Study) https://ClinicalTrials.gov/show/NCT01790841 Completed Biotronik SE & Co. KG 2015-05-31
NCT01736618 S-ICD® System Post Approval Study https://ClinicalTrials.gov/show/NCT01736618 Active, not recruiting Boston Scientific Corporation 2021-10-31
NCT01638897 DF4 Connector System Post-Approval Study https://ClinicalTrials.gov/show/NCT01638897 Completed Medtronic 2019-03-31
NCT01599065 Comparison of a MAGNET Protocol Versus “off-on” Protocol for Patients With Implantable Cardioverter Defibrillators https://ClinicalTrials.gov/show/NCT01599065 Completed Midwest Heart Foundation 2013-10-31
NCT01318746 The Circadian Rhythm of Potassium and Cystatin C https://ClinicalTrials.gov/show/NCT01318746 Completed University of Erlangen-Nürnberg Medical School 2013-04-30
NCT01326624 Study of the Wearable Defibrillator in Heart-Failure Patients https://ClinicalTrials.gov/show/NCT01326624 Completed Zoll Medical Corporation 2017-12-31
NCT04402268 Efficacy of Risk Assessment for Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy https://ClinicalTrials.gov/show/NCT04402268 Completed Poznan University of Medical Sciences 2018-09-01
NCT04368637 Acute Cardiovascular Events Triggered by COVID-19-Related Stress https://ClinicalTrials.gov/show/NCT04368637 Recruiting Jordan Collaborating Cardiology Group 2020-07-30
NCT04127643 Prospective Clinical Registry of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) (S-ICD Korea Registry) https://ClinicalTrials.gov/show/NCT04127643 Recruiting Yonsei University 2022-10-31
NCT04036799 PRecIsion Medicine in CardiomyopathY https://ClinicalTrials.gov/show/NCT04036799 Active, not recruiting The Hospital for Sick Children 2020-12-31
NCT04024865 Domperidone and Risk of Serious Cardiac Events in Postpartum Women https://ClinicalTrials.gov/show/NCT04024865 Completed Canadian Network for Observational Drug Effect Studies, CNODES 2019-07-31
NCT03910725 Electrophysiological Phenotyping Of Patients at Risk of Ventricular Arrhythmia and Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT03910725 Recruiting Imperial College London 2021-12-31
NCT03833843 Sudden Cardiac Death in Systemic Right Ventricle https://ClinicalTrials.gov/show/NCT03833843 Recruiting European Georges Pompidou Hospital 2019-09-01
NCT03784586 Sudden Cardiac Death Stratification in Myotonic Dystrophy Type 1 Patients https://ClinicalTrials.gov/show/NCT03784586 Recruiting University of Campania “Luigi Vanvitelli” 2022-06-30
NCT03715790 Improve SCA Bridge Study https://ClinicalTrials.gov/show/NCT03715790 Recruiting Medtronic Cardiac Rhythm and Heart Failure 2021-04-30
NCT03642405 Drug-induced Repolarization ECG Changes https://ClinicalTrials.gov/show/NCT03642405 Active, not recruiting Copenhagen University Hospital at Herlev 2019-09-03
NCT03590730 Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy https://ClinicalTrials.gov/show/NCT03590730 Recruiting Keimyung University Dongsan Medical Center 2020-11-15
NCT03526302 TroponinT After Subcutaneous Cardioverter-Defibrillator Implantation https://ClinicalTrials.gov/show/NCT03526302 Recruiting Deutsches Herzzentrum Muenchen 2020-06-30
NCT03493516 Prediction of ARrhythmic Events With Positron Emission Tomography II https://ClinicalTrials.gov/show/NCT03493516 Recruiting State University of New York at Buffalo 2022-12-31
NCT03485079 A Prospective,Multiple Center,Cohort Study of Prediction Model on Sudden Cardiac Death and Devices Development by Automatic Analysis From 24h Electrocardiogram in China https://ClinicalTrials.gov/show/NCT03485079 Enrolling by invitation Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 2022-12-31
NCT01262508 Development of Algorithms to Predict Hemodynamic Instability https://ClinicalTrials.gov/show/NCT01262508 Completed Heinrich-Heine University, Duesseldorf 2015-04-30
NCT01227785 Next Generation INCEPTA Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy (CRT-D) Field Following Study https://ClinicalTrials.gov/show/NCT01227785 Completed Guidant Corporation 2011-12-31
NCT01214460 Impact of Medical Emergency Team and EMS in Tampere University Hospital https://ClinicalTrials.gov/show/NCT01214460 Completed Tampere University Hospital 2016-07-31
NCT01209494 An Arrhythmia Risk Stratification and Genetic Trial https://ClinicalTrials.gov/show/NCT01209494 Completed University Medical Center Goettingen 2014-02-28
NCT01114269 PRE-DETERMINE Cohort Study https://ClinicalTrials.gov/show/NCT01114269 Active, not recruiting Brigham and Women’s Hospital 2021-02-28
NCT01102153 Neuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT01102153 Completed University of Leipzig 2010-01-31
NCT01076660 Left Ventricular Structural Predictors of Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT01076660 Recruiting Johns Hopkins University 2025-06-30
NCT00926159 Assessment of Appropriate ICD Implantation for Primary Prevention of Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT00926159 Completed University of Minnesota Physicians Heart at Fairview 2010-03-31
NCT00925457 Evaluating the Risk of Serious Ventricular Arrhythmia and Sudden Cardiac Death Among Users of Domperidone https://ClinicalTrials.gov/show/NCT00925457 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2009-03-31
NCT00920244 In-hospital Cardiac Arrest - Dynamics and State Transitions https://ClinicalTrials.gov/show/NCT00920244 Completed St. Olavs Hospital 2015-04-30
NCT00918125 Educational Videos to Improve Patient Decision Making and Race Disparities in Implantable Cardioverter Defibrillator Use https://ClinicalTrials.gov/show/NCT00918125 Completed Duke University 2012-04-30
NCT00916435 Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms https://ClinicalTrials.gov/show/NCT00916435 Completed Johns Hopkins University 2011-12-31
NCT00874445 Comparison of 50% Tilt and Tuned Waveforms in Single-Coil Active Can Configuration https://ClinicalTrials.gov/show/NCT00874445 Completed Abbott Medical Devices 2010-09-30
NCT00848835 Long Term Integrity Follow-up Evaluation https://ClinicalTrials.gov/show/NCT00848835 Completed Guidant Corporation 2009-10-31
NCT03962361 New Biomarkers of Neurological Outcome After a Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT03962361 Active, not recruiting Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2019-09-30
NCT01594112 Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators. https://ClinicalTrials.gov/show/NCT01594112 Completed Biotronik SE & Co. KG 2013-09-27
NCT00940888 SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator Patients https://ClinicalTrials.gov/show/NCT00940888 Completed Abbott Medical Devices 2015-09-30
NCT00733590 Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention https://ClinicalTrials.gov/show/NCT00733590 Recruiting Johns Hopkins University 2021-03-31
NCT00664807 Medtronic Genetic Arrhythmia Markers for Early Detection (GAME Study) https://ClinicalTrials.gov/show/NCT00664807 Completed Medtronic Corporate Technologies and New Ventures 2009-04-30
NCT00661128 Evaluating the Genetic Factors That May Lead to Sudden Cardiac Arrest (The GenSCA Study) https://ClinicalTrials.gov/show/NCT00661128 Enrolling by invitation University of Washington 2020-08-31
NCT00661037 SAFEty of Two Strategies of ICD Management at Implantation https://ClinicalTrials.gov/show/NCT00661037 Completed Boston Scientific Corporation 2011-05-31
NCT00622453 Arrhythmias in Myotonic Muscular Dystrophy https://ClinicalTrials.gov/show/NCT00622453 Completed Indiana University 2006-01-31
NCT00621426 T-Wave Alternans in Dialysis Patients https://ClinicalTrials.gov/show/NCT00621426 Completed Northwestern University 2008-05-31
NCT00614718 Failure of Chronically Implanted Defibrillator Leads -Incidence and Management https://ClinicalTrials.gov/show/NCT00614718 Completed University Hospital, Basel, Switzerland 2004-01-31
NCT00580775 Study of Early Hormone Replacement Therapy on Risk Factors for Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT00580775 Completed Yale University 2008-07-31
NCT00439790 Sympathetic Nerve Activity and an Implantable Cardioverter Defibrillator in Heart Failure Patients https://ClinicalTrials.gov/show/NCT00439790 Completed University Hospital, Toulouse NA
NCT00399503 Assessment of Noninvasive Methods to Identify Patients at Risk of Serious Arrhythmias After a Heart Attack https://ClinicalTrials.gov/show/NCT00399503 Completed University of Calgary 2007-12-31
NCT00376532 Extracellular Matrix Marker of Arrhythmia Risk (EMMA) https://ClinicalTrials.gov/show/NCT00376532 Completed Thomas Jefferson University 2008-09-30
NCT00312624 Morphological Predictors of Sudden Cardiac Death in Patients With Known Cardiomyopathies https://ClinicalTrials.gov/show/NCT00312624 Completed University of Pittsburgh NA
NCT00241800 Medications and the Risk of Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT00241800 Completed Vanderbilt University Medical Center 2016-05-31
NCT00181233 Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk https://ClinicalTrials.gov/show/NCT00181233 Recruiting Johns Hopkins University 2021-06-30
NCT00102180 Drug-Induced Sudden Death & Ventricular Arrhythmia https://ClinicalTrials.gov/show/NCT00102180 Completed University of Pennsylvania 2008-11-30
NCT00064558 Genetic Determinants of Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT00064558 Completed Brigham and Women’s Hospital 2008-06-30
NCT00006501 Prognostic Significance of T Wave Alternans https://ClinicalTrials.gov/show/NCT00006501 Completed Columbia University 2009-12-31
NCT00006420 Minnesota Heart Survey - Mortality and Morbidity https://ClinicalTrials.gov/show/NCT00006420 Completed University of Minnesota 2006-06-30
NCT00006311 Anxiety and Vagal Control of the Heart in Coronary Disease https://ClinicalTrials.gov/show/NCT00006311 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005418 Epidemiology of Cardiotoxicity in Children With Cancer https://ClinicalTrials.gov/show/NCT00005418 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005367 Epidemiology of Long QTand Asian Sudden Death in Sleep https://ClinicalTrials.gov/show/NCT00005367 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005358 Thrombogenic Factors and Recurrent Coronary Events https://ClinicalTrials.gov/show/NCT00005358 Completed University of Rochester NA
NCT00005356 Novel Hemostatic Cardiac Risk Factors in Framingham https://ClinicalTrials.gov/show/NCT00005356 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005265 Natural History of Coronary Heart Disease https://ClinicalTrials.gov/show/NCT00005265 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005235 Heart Rate Variability and Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT00005235 Completed Columbia University 1993-09-30
NCT00005205 Incidence of Diabetes and Cardiovascular Disease in Mexican Americans https://ClinicalTrials.gov/show/NCT00005205 Completed The University of Texas Health Science Center at San Antonio NA
NCT00005202 Identifying High Risk Patients With Syncope https://ClinicalTrials.gov/show/NCT00005202 Completed National Heart, Lung, and Blood Institute (NHLBI) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03360227 Registry of Device Implantation https://ClinicalTrials.gov/show/NCT03360227 Recruiting Heinrich-Heine University, Duesseldorf 2030-12-31
NCT03319160 LifeVest Safety and Efficacy in Real Life Settings in France https://ClinicalTrials.gov/show/NCT03319160 Completed Zoll Medical Corporation 2018-09-30
NCT04373876 Experience From the Italian S-ICD Registry https://ClinicalTrials.gov/show/NCT04373876 Recruiting Luigi Sacco University Hospital 2022-12-31
NCT04250857 HeartStart FRx Defibrillator Event Registry https://ClinicalTrials.gov/show/NCT04250857 Recruiting Philips Clinical & Medical Affairs Global 2021-12-31
NCT04189822 Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank https://ClinicalTrials.gov/show/NCT04189822 Enrolling by invitation University of British Columbia 2025-12-31
NCT03969797 AED Log Analysis of 19 Cases in Out-of-hospital Environment https://ClinicalTrials.gov/show/NCT03969797 Completed RadianQbio 2018-10-08
NCT03963271 Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrillation. https://ClinicalTrials.gov/show/NCT03963271 Enrolling by invitation Maastricht University Medical Center 2023-04-10
NCT03957824 PREVENTION-ACHD Risk Score https://ClinicalTrials.gov/show/NCT03957824 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2015-12-31
NCT03837574 French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator https://ClinicalTrials.gov/show/NCT03837574 Recruiting Paris Sudden Death Expertise Center 2019-08-01
NCT03801681 ARrhythmias in MYocarditis https://ClinicalTrials.gov/show/NCT03801681 Recruiting Medical University of Warsaw 2020-12-31
NCT03714048 Blood Management During ECMO for Cardiac Support https://ClinicalTrials.gov/show/NCT03714048 Recruiting St Vincent’s Hospital, Sydney 2021-07-31
NCT03642587 Canadian Sudden Cardiac Arrest Network https://ClinicalTrials.gov/show/NCT03642587 Recruiting St. Michael’s Hospital, Toronto 2020-06-30